Cover art featured as front cover of Small Special Issue "Synthetic Biology and Biomimicry"!
We are pleased to see our cover art being featured as front cover of Small in the Special Issue "Synthetic Biology and Biomimicry"
We developed a reusable biomolecular signaling platform comprising catalytic nanocompartments whose geometrical arrangement enabled effective communication. The chip promoted transfer of signals between neighboring nanocompartments and thereby triggered a complex cascade reaction (DNA synthesis, inorganic pyrophosphate (PPi), and adenosine triphosphate (ATP) production) that ultimately produced light. The simple removal and reloading of catalytic compartments rendered the platform suitable for multiple cycles of cascade reactions. We demonstrated that polymer-based nano-compartment assemblies offer an ideal scaffold for the development of the next generation responsive and communicative soft-matter analytical devices for applications in catalysis and medicine.