Welcome to the Biointerfaces Group of Cornelia G. Palivan!
We study soft bio-hybrid materials resulting from the combination of biomolecules with synthetic assemblies at the nano- and micro-scale. The goal of our research is to probe and understand the relation between the components of bio-hybrid materials as well as the biointerface of such materials with cells or simple animal models. The main questions that guide our research are: How can biomolecules preserve their function in a synthetic environment? How to modify biomolecules to induce new functionality and how is this affected when a bio-hybrid material is designed? How to self-organize bio-hybrid assemblies in more complex architectures to provide multifunctionality? Which are the interactions of bio-hybrid materials with cells? How to produce a new bio-hybrid material with desired functionality for specific applications? Our interest extends from fundamental understanding at the molecular level of such bio-hybrid materials and associated biointerfaces to technological and medical applications.
From spherical compartments to polymer films: exploiting vesicle fusion to generate solid supported thin polymer membranes
M. Kyropoulou, S. Y. Avsar, C.-A. Schoenenberger, C. G. Palivan, W. P. Meier
Nanoscale, 2021. DOI: 10.1039/d1nr01122g
AQP1 Is Up-Regulated by Hypoxia and Leads to Increased Cell Water Permeability, Motility, and Migration in Neuroblastoma
Z. Huo, M. Lomora, U. Kym, C. Palivan, S. G. Holland-Cunz, S. J. Gros
Frontiers in Cell and Developmental Biology, 2021. DOI: 10.3389/fcell.2021.605272
Immobilization of arrestin-3 on different biosensor platforms for evaluating GPCR binding
S. Yorulmaz Avsar, L.E. Kapinos, C.-A. Schoenenberger, G. F. X Schertler, J. Mühle, B. Meger, R. Y. H. Lim, M. K. Ostermaier, E. Lesca, C. G. Palivan
Phys Chem Chem Phys, 2020.DOI: 10.1039/d0cp01464h.