Welcome to the Biointerfaces Group of Cornelia G. Palivan!

 

We study soft bio-hybrid materials resulting from the combination of biomolecules with synthetic assemblies at the nano- and micro-scale. The goal of our research is to probe and understand the relation between the components of bio-hybrid materials as well as the biointerface of such materials with cells or simple animal models. The main questions that guide our research are: How can biomolecules preserve their function in a synthetic environment? How to modify biomolecules to induce new functionality and how is this affected when a bio-hybrid material is designed? How to self-organize bio-hybrid assemblies in more complex architectures to provide multifunctionality? Which are the interactions of bio-hybrid materials with cells? How to produce a new bio-hybrid material with desired functionality for specific applications? Our interest extends from fundamental understanding at the molecular level of such bio-hybrid materials and associated biointerfaces to technological and medical applications.


Latest Publications

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Multicomponent Copolymer Planar Membranes with Nanoscale Domain Separation
M. Bina, A. Krywko-Cendrowska, D. Daubian, W. Meier, C. G. Palivan,
Nano Letters, 2022, DOI: 10.1021/acs.nanolett.2c00332

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A self-assembling peptidic platform to boost the cellular uptake and nuclear delivery of oligonucleotides
S.Tarvirdipour,M. Skowicki, C.-A. Schoenenberger, L. E. Kapinos, R. Y. H. Lim, Y. Benenson, C. G. Palivan
Biomater. Sci., 2022, DOI: 10.1039/D2BM00826B

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Current Perspectives on Synthetic Compartments for Biomedical Applications
L. Heuberger, M. Korpidou, O.M. Eggenberger, M. Kyropoulou, C.G. Palivan
Int. J. Mol. Sci.2022, 23, 5718. DOI: 10.3390/ijms23105718

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Tailoring a Solvent-Assisted Method for Solid-Supported Hybrid Lipid−Polymer Membranes
S. Di Leone, M. Kyropoulou, J. Köchlin, R. Wehr, W. P. Meier, C. G. Palivan
Langmuir, 2022, DOI: 10.1021/acs.langmuir.2c00204

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Block Copolymer Giant Unilamellar Vesicles for High-Throughput Screening
L. Heuberger, C. G. Palivan
CHIMIA, 2022, DOI: 10.2533/chimia.2022.350