Welcome to the Biointerfaces Group of Cornelia G. Palivan!

 

We study soft bio-hybrid materials resulting from the combination of biomolecules with synthetic assemblies at the nano- and micro-scale. The goal of our research is to probe and understand the relation between the components of bio-hybrid materials as well as the biointerface of such materials with cells or simple animal models. The main questions that guide our research are: How can biomolecules preserve their function in a synthetic environment? How to modify biomolecules to induce new functionality and how is this affected when a bio-hybrid material is designed? How to self-organize bio-hybrid assemblies in more complex architectures to provide multifunctionality? Which are the interactions of bio-hybrid materials with cells? How to produce a new bio-hybrid material with desired functionality for specific applications? Our interest extends from fundamental understanding at the molecular level of such bio-hybrid materials and associated biointerfaces to technological and medical applications.


Latest Publications

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Membrane protein channels equipped with a cleavable linker for inducing catalysis inside nanocompartments
L. Zartner, V. Maffeis, C.A. Schoenenberger, I.A. Dinu, C.G. Palivan
J. Mater. Chem. B, 2021, DOI: 10.1039/D1TB01463C

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Artificial Melanogenesis by Confining Melanin/Polydopamine Production inside Polymersomes
C. E. Meyer, C. A. Schoenenberger, R. P. Wehr, D. Wu, C. G. Palivan
Macromolecular Bioscience 2021. DOI: 10.1002/mabi.202100249

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Clustering of catalytic nanocompartments for enhancing an extracellular non-native cascade reaction
V. Maffeis, A. Belluati, I. Craciun, D. Wu, S. Novak, C.-A. Schoenenberger, C. G. Palivan
Chem. Sci. 2021. DOI: 10.1039/D1SC04267J

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Peptide-Assisted Nucleic Acid Delivery Systems on the Rise
S. Tarvirdipour, M. Skowicki, C-A. Schoenenberger, C. G. Palivan
Int. J. Mol. Sci., 2021, 22(16), pp. 9092- 9122. DOI: 10.3390/ijms22169092

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DNA-tethered Polymersomes Clusters as Nanotheranostic Platform
C.E. Meyer, C-A Schoenenberger, J. Liu, C. Craciun, C.G. Palivan
Chimia, 2021. DOI: 10.2533/chimia.2021.296