Piotr Jasko
General Information
Department of Chemistry
University of Basel
Mattenstrasse 24a, BPR-1096
4058 Basel, Switzerland
phone: +41 61 207 38 32
email: piotr.jasko@clutterunibas.ch
Projects
Developing artificial systems based on polymeric compartments
Biophysical investigation of bacterial toxin component in lipidic membrane fusion - PD Dr. Richard Kammerer (PSI)
Establishing novel frontiers in giant plasma membrane vesicles (GPMVs) application - Prof. Dr. med. Stephanie Gros (UKBB)
The projects are conducted under the umbrella of the Swiss Nanoscience Institute.
CV
Research Experience
- 03.2021 - present: PhD student
University of Basel – Department of Chemistry
Paul Scherrer Institut – Laboratory of Biomolecular Research
UKBB – Group of Molecular Therapeutic Strategies in Pediatric Surgery
- 2020: ERASMUS+ Intern/Research associate
Technical University of Munich, Germany
Bavarian NMR Center at the Dep. of Chemistry
Lab of Structural Membrane Biochemistry
- 04.2018 - 09.2018: ERASMUS+ Intern
Rheinische Friedrich-Wilhelms-Universität Bonn, Germany
Pharmaceutical Institute
Department of Pharmaceutical & Medicinal Chemistry
- 01.2018 - 03.2018: Intern
University Hospital of Munich, Germany
Department of Medicine III
Experimental Leukemia and Lymphoma Research Group (ELLF)
Education
Jagiellonian University Collegium Medicum in Krakow, Poland
Faculty of Pharmacy
Medical Analytics (MSc)
Thesis in pharmacodynamics: Cardiovascular safety assessment of (R)-KA-104 compound
Jagiellonian University in Krakow, Poland
Faculty of Biochemistry, Biophysics and Biotechnology
Biochemistry (BSc)
Thesis in physical biochemistry: Cell membrane models based on nanodisc systems
- Erasmus+
Ludwig Maximilians Universität München, Germany
Faculty of Biology
Biology/Biochemistry (BSc)
Publications
A coiled-coil-based design strategy for the thermostabilization of G-protein-coupled receptors [link]
M. Amer, O. Leka, P. Jasko, D. Frey, X. Li, R. A. Kammerer
Sci Rep 2023; 13, 10159 doi:10.1038/s41598-023-36855-1
Advances in Biohybridized Planar Polymer Membranes and Membrane-Like Matrices [link]
O. M. Eggenberger, P. Jaśko, S. Tarvirdipour, C.-A. Schoenenberger, C. G. Palivan
Helv. Chim. Acta 2023, e202200164 doi:10.1002/hlca.202200164
8-Benzylaminoxanthine scaffold variations for selective ligands acting on adenosine A2A receptors.Design, synthesis and biological evaluation [link]
M. Załuski, J. Schabikowski, P. Jaśko, A. Bryła, A. Olejarz-Maciej, M. Kaleta, M. Głuch-Lutwin, A. Brockmann, S. Hinz, M. Zygmunt, K. Kuder, G. Latacz, C. Vielmuth, C.E. Müller, K. Kieć-Kononowicz
Bioorg Chem 2020;101:104033 doi:10.1016/j.bioorg.2020.104033
Novel, dual target-directed annelated xanthine derivatives acting onadenosine receptors and monoamine oxidase B [link]
K. J. Kuder, M. Załuski, J. Schabikowski, G. Latacz, A. Olejarz-Maciej, P. Jaśko, A. Doroz-Płonka, A. Brockmann, C. E. Müller, K. Kieć-Kononowicz.
ChemMedChem 2020;15(9):772-786 doi:10.1002/cmdc.201900717